Polyglutamic acid: your skin's new ally

Acide Polyglutamique : le nouvel allié de votre peau - NUXE

Polyglutamic Acid has now established itself as a highly sought-after active ingredient in cosmetics. Still relatively unknown to the general public, it nevertheless delivers remarkable performance in hydration, plumpness and overall skin quality. At NUXE, this exceptional ingredient lies at the heart of the new Prodigieuse® [Hyalu] Boost collection, a range of over-activated skincare products designed to deliver expert dual-level hydration and reveal visibly more beautiful skin.

Where can Polyglutamic Acid be found?


Polyglutamic Acid is a polypeptide derived from the fermentation of certain bacteria. Studied for its water-retention properties (it can hold up to 5,000 times its weight in water(1)), it quickly attracted the interest of cosmetic research for its exceptional ability to maintain optimal skin hydration. Polyglutamic Acid is not naturally present in the skin, but it is a powerful active ingredient suitable for all skin types.

What are the benefits of Polyglutamic Acid?


If Polyglutamic Acid is attracting so much attention, it is because of its unique ability to improve skin quality(2). High molecular weight Polyglutamic Acid:


  • Hydrates the skin.

  • Strengthens the skin barrier.

  • Inhibits the activity of the molecule that degrades the Hyaluronic Acid naturally present in the skin.


Skin looks plumper and more radiant. Dehydration lines are smoothed, the skin is better protected against external aggressors and feels softer and more comfortable.

Our Polyglutamic Acid products


Polyglutamic Acid is part of the expert multi-molecular hydrating duo at the heart of Prodigieuse® [Hyalu] Boost skincare.

Dual-level hydration


The over-activated skincare products in the Prodigieuse® [Hyalu] Boost collection incorporate an expert multi-molecular hydrating duo(3):


  • The low molecular weight Hyaluronic Acid, known for hydrating the skin and improving elasticity.


  • The high molecular weight Polyglutamic Acid, to plump the skin and strengthen the skin barrier.


This expert hydration approach, designed on two complementary levels, delivers visible results in radiance, comfort and skin bounce. Transepidermal water loss is limited, helping preserve the skin’s natural glow.

Prodigieuse® [Hyalu] Boost, the over-activated collection


The Prodigieuse® [Hyalu] Boost skincare range comes in irresistible textures to help all skin types preserve or restore their glow*.

The Anti-Dark Spot Radiance Serum

The expert multi-molecular hydrating duo is combined with 5% stabilized Vitamin C to hydrate, boost skin radiance, reduce dark spots and even out the complexion. Achieve a glass skin** effect.

The Illuminating Concentrate

This hybrid serum combines dual-level hydration with instant radiance. Its secret? A high concentration of expert active ingredients paired with rosy natural pearls. Skin is instantly enhanced, twice as luminous.

The Plumping Radiance Cream

This over-activated cream is ideal for normal to dry skin seeking comfort, bounce and radiance. Its enveloping, non-greasy texture smooths dehydration lines and leaves skin plumped.

The Smoothing Radiance Gel-Cream

Dedicated to normal to combination skin, this over-activated formula refines and smooths skin texture while boosting radiance.

The Night Recovery Balm-Oil

Experience dual-level hydration in a comforting texture effective from the very first night. Skin quality improves, features look relaxed. Night after night, the “baby skin” effect leaves skin smooth, nourished, plump and radiant.

The De-Puffing Eye Stick

This treatment with an immediate cooling effect combines low molecular weight Hyaluronic Acid with Caffeine to refresh and smooth the eye contour. Its innovative stick format reinvents application, reducing puffiness and dark circles for a smoother, more hydrated and brighter-looking eye area.

Why choose NUXE?

NUXE represents expert, sensorial skincare inspired by nature. For over 30 years, our laboratory has been developing products that combine scientific innovation, reference active ingredients and a true pleasure of use.

With Prodigieuse® [Hyalu] Boost, NUXE invites you to discover dual hydration thanks to a duo of expert actives. Our over-activated formulas with low molecular weight Hyaluronic Acid and high molecular weight Polyglutamic Acid leave skin radiant, supple and plump.

Each application becomes a moment of well-being, a sensory escape. Our formulas melt into the skin to deliver their benefits along with a sparkling fragrance blending Lychee, Jasmine and White Musk.

A high-performance active ingredient, high molecular weight Polyglutamic Acid is an essential ally for skin hydration. Able to retain water, protect the Hyaluronic Acid naturally present in the skin and strengthen the skin barrier, it lies at the heart of the over-activated Prodigieuse® [Hyalu] Boost formulas. Combined with low molecular weight Hyaluronic Acid, it forms an expert duo capable of delivering dual-level hydration. Skin looks plump and radiant.

*Glow = radiance.

** Glass skin = smooth, luminous, even-looking complexion.

(1) CBC Life

(2) M. Serra et al. (2024)

(3) In all Prodigieuse® [Hyalu] Boost skincare products except the De-Puffing Eye Stick.

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